產(chǎn)品編號(hào) |
bs-13362R-HRP |
英文名稱 |
Rabbit Anti-GJA10/HRP Conjugated antibody
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中文名稱 |
辣根過(guò)氧化物酶標(biāo)記的間隙連接蛋白10抗體 |
別 名 |
Gap junction alpha 10; Connexin-62; Cx62; CXA10_HUMAN; Gap junction alpha 10; Gap junction alpha 10 protein; Gap junction alpha-10 protein; Gap junction protein alpha 10 59kDa; GJA10; MGC50985; RP11-63K6.6;
Gap junction alpha 10;
Connexin 58;
Connexin 59;
Connexin-62;
CX58;
CX59;
Cx62;
CXA10_HUMAN;
Gap junction alpha 10;
Gap junction alpha 10 protein;
Gap junction alpha 9 protein;
Gap junction alpha-10 protein;
Gap junction protein alpha 10 59kDa;
Gap junction protein alpha 9 59kDa;
GJA10;
MGC50985. |
規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) |
100ul
|
研究領(lǐng)域 |
心血管 細(xì)胞生物 細(xì)胞粘附分子 |
抗體來(lái)源 |
Rabbit |
克隆類型 |
Polyclonal |
交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Chicken, Cow, Rabbit, Sheep, )
|
產(chǎn)品應(yīng)用 |
ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
分 子 量 |
62kDa |
性 狀 |
Lyophilized or Liquid |
濃 度 |
1mg/ml |
免 疫 原 |
KLH conjugated synthetic peptide derived from human GJA10 |
亞 型 |
IgG |
純化方法 |
affinity purified by Protein A |
儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008].
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning.
Subunit: A connexon is composed of a hexamer of connexins.
Subcellular Location: Cell membrane. Cell junction; gap junction.
Tissue Specificity: Expressed in skeletal muscle and heart.
Similarity: Belongs to the connexin family. Alpha-type (group II) subfamily.
Database links:
UniProtKB/Swiss-Prot: Q969M2.1
Entrez Gene: 84694 Human
Omim: 611924 Human
SwissProt: P57773 Human
SwissProt: Q969M2 Human
Unigene: 334499 Human
Unigene: 632402 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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