| 產(chǎn)品編號 |
bs-5205R-BF350 |
| 英文名稱 |
Rabbit Anti-Phospho-ATG4C(Ser398)/BF350 Conjugated antibody
|
| 中文名稱 |
BF350標(biāo)記的磷酸化自噬相關(guān)蛋白4C抗體 |
| 別 名 |
APG4 autophagy 4 homolog C (S. cerevisiae); APG4 autophagy 4 homolog C; APG4 C; APG4-C; APG4C; ATG 4C; ATG4 autophagy related 4 homolog C (S. cerevisiae); Atg4c; ATG4C_HUMAN; AUT (S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase (S. cerevisiae); AUT like 1, cysteine endopeptidase; AUT like 3 cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; Autophagin 3; Autophagin-3; Autophagy related cysteine endopeptidase 3; Autophagy related protein 4 homolog C; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; Cysteine protease ATG4C; EC 3.4.22; FLJ14867; OTTHUMP00000010715. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 產(chǎn)品類型 |
磷酸化抗體 |
| 研究領(lǐng)域 |
腫瘤 心血管 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 激酶和磷酸酶 線粒體 泛素 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
Mouse,
(predicted: Human, Rat, Dog, Pig, Cow, )
|
| 產(chǎn)品應(yīng)用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
52kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated Synthesised phosphopeptide derived from human ATG4C around the phosphorylation site of Ser398 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Function:
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Subcellular Location:
Cytoplasm (Probable).
Tissue Specificity:
Highly expressed in skeletal muscle, heart, liver and testis.
Similarity:
Belongs to the peptidase C54 family.
Database links:
Entrez Gene: 84938 Human
Entrez Gene: 242557 Mouse
Entrez Gene: 313391 Rat
Omim: 611339 Human
SwissProt: Q96DT6 Human
SwissProt: Q811C2 Mouse
Unigene: 7353 Human
Unigene: 241663 Mouse
Unigene: 23378 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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