| 產(chǎn)品編號 |
bs-11533R-BF647 |
| 英文名稱 |
Rabbit Anti-PCSK2/Proprotein Convertase 2/BF647 Conjugated antibody
|
| 中文名稱 |
BF647標(biāo)記的神經(jīng)內(nèi)分泌轉(zhuǎn)化酶2抗體 |
| 別 名 |
KEX2 like endoprotease 2; KEX2-like endoprotease 2; NEC 2; NEC2; NEC2_HUMAN; Neuroendocrine convertase 2; PC2; PCSK2; Prohormone convertase 2; Proprotein convertase 2; Proprotein convertase subtilisin/kexin type 2; SPC2. |
| 規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
| 說 明 書 |
100ul
|
| 研究領(lǐng)域 |
細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 生長因子和激素 |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
Mouse, Rat,
(predicted: Human, Chicken, Dog, Cow, Sheep, )
|
| 產(chǎn)品應(yīng)用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
58kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human Proprotein Convertase 2 (201-300aa) |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
Function:
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.
Subcellular Location:
Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules.
Similarity:
Belongs to the peptidase S8 family. Furin subfamily.
Database links:
Entrez Gene: 5126 Human
Entrez Gene: 18549 Mouse
Omim: 162151 Human
SwissProt: P16519 Human
SwissProt: P21661 Mouse
Unigene: 315186 Human
Unigene: 294493 Mouse
Unigene: 447466 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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