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Mouse Transglutaminase 2 Ready-To-Use IHC Kit (IHC0437M)  
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產(chǎn)品編號 IHC0437M
英文名稱 Mouse Transglutaminase 2 Ready-To-Use IHC Kit
中文名稱 小鼠谷氨酰胺轉胺酶2即用型免疫組化試劑盒
別    名 TG 2; TG(C); TG2; TGase C; TGase H; TGase-2; TGase2; TgaseII; ALPHA SUBUNIT; C polypeptide; G alpha h; G protein alpha subunit Gh class; G[a]h; Gh CLASS G ALPHA h; GNAH; GNAH G PROTEIN; Guanine nucleotide binding protein H polypeptide; H POLYPEPTIDE; Prot  
適用樣品基質 FFPE tissue
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
產(chǎn)品介紹 Transglutaminase (TGase) catalyses the crosslink of proteins by forming e-(g-glutamyl) lysine isopeptide bonds and requires the binding of Ca2+ for its activity. In mammals, eight distinct TGase isoenzymes have been identified. Tissue transglutaminase (tTGase), also known as TGase 2, has four distinct domains: N-terminal b-sandwich, catalytic core and two C-terminal b-barrel domains. tTGase may have a role in cell death, cell proliferation, cell differentiation, and receptor-mediated endocytosis. In the Alzheimer's disease brain, the elevated tTGase activity is manifested by polymerization of a number of proteins, including Ab peptide, b-amyloid precursor protein and the tau protein, with formation of neurofibrillary tangles.

SWISS:
P21980

Gene ID:
7052

產(chǎn)品圖片
Immunohistochemical analysis of paraffin embedded mouse lung tissue slide using IHC0437M (Mouse Transglutaminase 2 IHC Kit).
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