| 產(chǎn)品編號 | D58223 |
| 英文名稱 | CLK1-IN-3 |
| 中文名稱 | CLK1抑制劑3 |
| CAS | 2922550-28-3 |
| 理論分子量 | 430.48 kDa |
| 檢測分子量 | |
| 保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A. CLK1-IN-3 also showed highly effective inhibition of Clk2 and Clk4, with IC50 values of 42 and 108 nM, respectively. CLK1-IN-3 is effective in inducing autophagy in vitro and can be used for prevention and human treatment of acute liver injury (ALI). |
