產(chǎn)品編號(hào) | D58180 |
英文名稱 | WWL123 |
中文名稱 | |
CAS | 1338575-41-9 |
理論分子量 | 436.5 kDa |
檢測(cè)分子量 | |
保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
WWL123 is a potent and selective ABHD6 inhibitor (IC50=430 nM). WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole (PTZ)-induced epileptiform seizures and spontaneous seizures in R6/2 mice. |