| 產(chǎn)品編號 | V0408-BF488 |
| 英文名稱 | Human IL-6 Mouse mAb, BF488 conjugated |
| 中文名稱 | BF488標(biāo)記的白介素6單克隆抗體 |
| 別 名 | Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma plasmac |
| 克 隆 號 | 4D1 |
| 理論分子量 | kDa |
| 檢測分子量 | |
| 緩 沖 液 | 0.01M PBS(pH7.4). |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]. 白細(xì)胞介素6是一種多功能細(xì)胞因子，既可由淋巴細(xì)胞產(chǎn)生，也能由非淋巴細(xì)胞合成。在體內(nèi)免疫反應(yīng)調(diào)節(jié)、血細(xì)胞的增生、防御機(jī)制和急性期反應(yīng)中起重要作用。 白細(xì)胞介素-6是一種糖蛋白，它既可誘導(dǎo)急性期時相關(guān)蛋白的產(chǎn)生，也是β細(xì)胞終末分化并分泌抗體的必需因子，在免疫調(diào)節(jié)中發(fā)揮重要作用，人的IL-6的前體有212個氨基酸。成熟形態(tài)為185個氨基酸。白細(xì)胞介素6的分子量：21KD-28KD |
