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PD-L1 Mouse mAb (bsm-43073M)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
200ug(PBS only)/5600.00元
大包裝/詢價

產(chǎn)品編號 bsm-43073M
英文名稱 PD-L1 Mouse mAb
中文名稱 人程序性死亡配體1單克隆抗體
別    名 Programmed cell death 1 ligand 1; CD274; B7 H; B7 H1; B7 homolog 1; B7-H1; B7H; B7H1; CD 274; CD274 antigen; CD274 molecule; MGC142294; MGC142296; OTTHUMP00000021029; PD L1; PD1L1_HUMAN; PD1L1_Mouse; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL 1; PDL1; Programmed death ligand 1; RGD1566211.  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導  細胞凋亡  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 3B11
交叉反應 Human
產(chǎn)品應用 WB=1:500-2000,Flow-Cyt=1ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human PD-L1 protein: 15-239/290 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

SWISS:
Q9NZQ7

Gene ID:
29126

Database links:

Entrez Gene: 29126 Human

Entrez Gene: 60533 Mouse

Omim: 605402 Human

SwissProt: Q9NZQ7 Human

SwissProt: Q9EP73 Mouse

Unigene: 521989 Human

Unigene: 245363 Mouse



產(chǎn)品圖片
Sample: Lane 1: Human MDA-MB-231 cell lysates Primary: Anti-Human PD-L1 (bsm-43073M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti- Mouse IgG at 1/20000 dilution Predicted band size: 29 kDa Observed band size: 53 kDa
Blank control(black line):MDA-MB-231. Primary Antibody (green line): Mouse Anti-Human PD-L1 antibody (bsm-43073M) Dilution:1ug/Test; Secondary Antibody(white blue line): Goat anti-mouse IgG-FITC Dilution: 0.5ug/Test. Isotype control(orange line): No
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