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CALCA Mouse mAb (bsm-51512M)  
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產品編號 bsm-51512M
英文名稱 CALCA Mouse mAb
中文名稱 降鈣素單克隆抗體
別    名 Katacalcin; Calcitonin; alpha CGRP; CALC 1; CALC A; CALC1; Calcitonin related polypeptide alpha; CGRP 1; CGRP; CGRP I; CGRP-1; CGRPI; CGRP1; CT; KC; MGC126648; alpha type CGRP; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related peptide I; calcitonin isoform CT preproprotein; CALC_HUMAN.  
研究領域 腫瘤  神經生物學  生長因子和激素  內分泌病  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 G8D24
交叉反應 Human
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 2/13 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CALCA: 51-130/141 
亞    型 IgM
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.

Function:
Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Katacalcin is a potent plasma calcium-lowering peptide

Subcellular Location:
Secreted.

Similarity:
Belongs to the calcitonin family.

SWISS:
P01258

Gene ID:
796

Database links:

Entrez Gene: 796 Human

SwissProt: P01258 Human





產品圖片
Sample: Lane 1: HL60 cell lysates Primary: Anti-CALCA (bsm-51512M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 2/13 kD Observed band size: 17 kD
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