產(chǎn)品編號 | bs-19776R |
英文名稱 | RBMS1/Cervical cancer oncogene 4 Rabbit pAb |
中文名稱 | 宮頸癌癌基因4抗體 |
別 名 | c myc gene single strand binding protein 2; C2orf12; Cervical cancer oncogene 4; HCC 4; MSSP 2; MSSP 3; MSSP; MSSP-1; MSSP-2; MSSP-3; MSSP1; RBMS1; RBMS1_HUMAN; RNA binding motif, single stranded interacting protein 1; RNA-binding motif; SCR2; Single stranded DNA binding protein MSSP 1; Single-stranded DNA-binding protein MSSP-1; single-stranded-interacting protein 1; suppressor of cdc 2(cdc13) with RNA binding motif 2; Suppressor of CDC2 with RNA binding motif 2; Suppressor of CDC2 with RNA-binding motif 2; YC1. |
研究領(lǐng)域 | 腫瘤 細(xì)胞凋亡 細(xì)胞周期蛋白 轉(zhuǎn)錄調(diào)節(jié)因子 結(jié)合蛋白 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 45 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human RBMS1/Cervical cancer oncogene 4: 181-280/406 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009] Function: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. Subcellular Location: Nucleus. Tissue Specificity: Highest amounts are found in placenta, lung and heart. Similarity: Contains 2 RRM (RNA recognition motif) domains. SWISS: P29558 Gene ID: 5937 Database links: Entrez Gene: 395880 Chicken Entrez Gene: 5937 Human Entrez Gene: 56878 Mouse GenBank: NP_058520.1 Human Omim: 602310 Human SwissProt: P29558 Human SwissProt: Q91W59 Mouse Unigene: 470412 Human Unigene: 708357 Human Unigene: 259667 Mouse Unigene: 482338 Mouse Unigene: 98522 Rat |
產(chǎn)品圖片 | |