產(chǎn)品編號(hào) | bs-19153R |
英文名稱 | Rabbit Anti-MYO10 antibody |
中文名稱 | 肌凝蛋白X抗體 |
別 名 | AW048724; D15Ertd600e; FLJ10639; FLJ21066; FLJ22268; FLJ43256; KIAA0799; MGC131988; mKIAA0799; MYO10; MYO10_HUMAN; Myosin X; Myosin-X; OTTMUSP00000022066; Unconventional myosin 10; Unconventional myosin X; Unconventional myosin-10. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 結(jié)合蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 237 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MYO10: 551-650/2058 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011] Function: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Plays a role in regions of dynamic actin. Subunit: May be in an inactive, monomeric conformation in the cytosol. Detected in cytoplasmic punctae and in cell projections. Colocalizes with actin fibers. Undergoes forward and rearward movements within filopodia. Interacts with microtubules. Similarity: Contains 1 FERM domain. Contains 3 IQ domains. Contains 1 myosin head-like domain. Contains 1 MyTH4 domain. Contains 2 PH domains. SWISS: Q9HD67 Gene ID: 4651 Database links: Entrez Gene: 4651 Human Entrez Gene: 17909 Mouse Omim: 601481 Human SwissProt: Q9HD67 Human SwissProt: F8VQB6 Mouse Unigene: 481720 Human |