| 產(chǎn)品編號(hào) | bs-19025R |
| 英文名稱 | Rabbit Anti-NAS6 antibody |
| 中文名稱 | 釀酒酵母NAS6蛋白抗體 |
| 別 名 | Nas6p; PSD10_YEAST; YGR232W; G8564; ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6; Probable 26S proteasome regulatory subunit p28; Proteasome interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle(RP); Proteasome non ATPase subunit 6. |
| 研究領(lǐng)域 | 微生物學(xué) 細(xì)菌及病毒 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Saccharomyces cerevisiae) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 26 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Saccharomyces cerevisiae NAS6: 41-140/228 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
NAS6 (p28) is a proteasome-interacting protein which acts as a chaperone to assemble the base sub-complex of the 19S RP which is involved in the ATP-dependent degradation of ubiquitinated proteins. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD. Function: Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14. Subunit: Interacts with RPT3. Subcellular Location: Cytosol; Nucleus; Proteasome complex Similarity: Contains 6 ANK repeats. Database links: Entrez Gene: 853147 Saccharomyces cerevisiae SwissProt: P50086 Saccharomyces cerevisiae |
