產(chǎn)品編號(hào) | bs-9909R |
英文名稱 | GGT6 Rabbit pAb |
中文名稱 | γ-谷氨酰轉(zhuǎn)肽酶6抗體 |
別 名 | gamma glutamyltransferase 6 homolog; gamma glutamyltranspeptidase 6; GGT 6; GGT6_HUMAN. |
研究領(lǐng)域 | 腫瘤 心血管 信號(hào)轉(zhuǎn)導(dǎo) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human,Mouse (predicted: Rat,Pig,Sheep,Horse) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 50 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GGT6: 321-420/493 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
GGT6 belongs to the gamma-glutamyltransferase family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis. GGT6 has very limited amino acid similarity to GGT1 and it's enzymatic activities are currently uncharacterized. GGT assays are of current widespread clinical use to help assess tissue damage. Function: Cleaves glutathione conjugates Subunit: Heterodimer composed of the light and heavy chains. The active site is located in the light chain (By similarity). Subcellular Location: Membrane; Single-pass type II membrane protein. Similarity: Belongs to the gamma-glutamyltransferase family. SWISS: Q6P531 Gene ID: 124975 Database links: Entrez Gene: 124975 Human Omim: 612341 Human SwissProt: Q6P531 Human Unigene: 130749 Human |
產(chǎn)品圖片 | |