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DHPS1 Rabbit pAb (bs-8260R)  
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產(chǎn)品編號(hào) bs-8260R
英文名稱 DHPS1 Rabbit pAb
中文名稱 短鏈脫氫還原酶1抗體
別    名 dehydrogenase/reductase(SDR family) member 1; Dehydrogenase/reductase SDR family member 1; FLJ25430; MGC20204; DHRS1_HUMAN.  
研究領(lǐng)域 心血管  細(xì)胞生物  免疫學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DHPS1: 1-100/313 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 DHRS1 (dehydrogenase/reductase (SDR family) member 1), also known as SDR19C1, is a 313 amino acid protein that belongs to the short-chain dehydrogenases/reductases (SDR) family and likely functions as an oxidoreductase. Abundantly expressed in heart and liver, DHRS1 contains an SDR motif and is encoded by a gene that maps to human chromosome 14q12. Human chromosome 14 houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.

Tissue Specificity:
Detected in heart and liver, and at low levels in skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

SWISS:
Q9UN19

Gene ID:
27071

Database links:

Entrez Gene: 27071 Human

Entrez Gene: 26377 Mouse

Entrez Gene: 362046 Rat

Omim: 605768 Human

SwissProt: Q9UN19 Human

SwissProt: Q9QXT1 Mouse

Unigene: 436271 Human

Unigene: 708484 Human

Unigene: 254835 Mouse

Unigene: 470427 Mouse

Unigene: 16615 Rat



產(chǎn)品圖片
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-DHPS1 (bs-8260R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34 kD Observed band size: 36 kD
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