| 產(chǎn)品編號(hào) | bs-8074R |
| 英文名稱 | ANKRD1 Rabbit pAb |
| 中文名稱 | 心肌錨蛋白重復(fù)結(jié)構(gòu)域1抗體 |
| 別 名 | ALRP; ANKR1_HUMAN; ANKRD 1; ANKRD1; Ankyrin repeat domain 1(cardiac muscle); Ankyrin repeat domain containing protein 1; Ankyrin repeat domain-containing protein 1; C 193; C193; Cardiac ankyrin repeat protein; CARP; CVARP; Cytokine inducible nuclear prote |
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Specific References (2) | bs-8074R has been referenced in 2 publications.
[IF=3.468] Konishi,et al.Proliferation of hepatic stellate cells, mediated by YAP and TAZ, contributes to liver repair and regeneration after liver ischemia-reperfusion injury.(2018) American Journal of Physiology. Gastrointestinal and Liver Physiology. 314:G471-G482. WB ; Mouse.
[IF=0.753] Hu,et al.Effect of EMD on the orthodontically induced root resorption repair process in rats.(2018) Journal of Orofacial Orthopedics. 79:83-95. IHC-P ; Rat.
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| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 36 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANKRD1: 185-319/319 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Function: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Subunit: Interacts with YBX1 (By similarity). Interacts with TTN/titin. Subcellular Location: Nucleus. Tissue Specificity: Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. DISEASE: Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return (TAPVR) . TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximately 1 out of 15'000 live births. Similarity: Contains 5 ANK repeats. SWISS: Q15327 Gene ID: 27063 Database links: Entrez Gene: 27063 Human Entrez Gene: 107765 Mouse Omim: 609599 Human SwissProt: Q15327 Human SwissProt: Q9CR42 Mouse Unigene: 448589 Human Unigene: 10279 Mouse Unigene: 3789 Rat |
