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S100 alpha 2 Rabbit pAb (bs-7873R)  
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產品編號 bs-7873R
英文名稱 S100 alpha 2 Rabbit pAb
中文名稱 S100A2抗體
別    名 S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN.  
Specific References  (1)     |     bs-7873R has been referenced in 1 publications.
[IF=1.39] Wu et al. A retrospective, single-center cohort study on 65 patients with primary retroperitoneal liposarcoma. (2018) Oncol.Lett. 15:1799-1810  IHC-P ;  Human.  
研究領域 腫瘤  細胞生物  信號轉導  細胞周期蛋白  結合蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Cat,Horse,Goat,lizard)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 11 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human S100 alpha 2: 20-98/98 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer.

Function:
May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth.

Subunit:
Homodimer. Interacts with FKBP4.

Tissue Specificity:
A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes.

Similarity:
Belongs to the S-100 family
Contains 2 EF-hand domains.

SWISS:
P29034.3

Gene ID:
6273

Database links:
UniProtKB/Swiss-Prot: P29034.3

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