| 產(chǎn)品編號(hào) | bs-7003R |
| 英文名稱 | Rabbit Anti-PMPCB antibody |
| 中文名稱 | 線粒體導(dǎo)肽水解酶β抗體 |
| 別 名 | beta MPP; betaMPP; Mitochondrial processing peptidase subunit beta; MPP11; MPPB; MPPP52; P 52; P52; Peptidase mitichondrial processing beta. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 腫瘤細(xì)胞生物標(biāo)志物 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PMPCB: 181-280/489 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
PMPCB is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. PMPCB is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. Function: Cleaves presequences (transit peptides) from mitochondrial protein precursors. Subunit: Heterodimer of alpha and beta subunits. Subcellular Location: Mitochondrion matrix. Similarity: Belongs to the peptidase M16 family. Gene ID: 9512 Database links: UniProtKB/Swiss-Prot: O75439.2 |
| 產(chǎn)品圖片 |
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-PMPCB Polyclonal Antibody, Unconjugated(bs-7003R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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