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Rabbit Anti-SDCCAG8  antibody (bs-7011R)  
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-7011R
英文名稱 Rabbit Anti-SDCCAG8  antibody
中文名稱 結(jié)腸癌抗原8抗體
別    名 Antigen NY CO 8; CCCAP; Centrosomal colon cancer autoantigen protein; HSPC085; NPHP10 gene; NY-CO-8; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; SLSN7 gene; SDCG8_HUMAN.  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導  細胞類型標志物  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 83 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SDCCAG8: 321-420/713 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The exact function of SDCCAG8 remains unknown. It is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.

Function:
Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). May play a role in ciliogenesis.

Subunit:
Homodimer (By similarity). Interacts with OFD1; the interaction is direct. Interacts with FAM161A.

Subcellular Location:
Isoform 2: Cytoplasm.

Tissue Specificity:
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.

DISEASE:
Defects in SDCCAG8 are the cause of Senior-Loken syndrome type 7 (SLSN7) [MIM:613615]. SLSN7 is a renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney (nephronophthisis), with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life.

SWISS:
Q86SQ7

Gene ID:
10806

Database links:

Entrez Gene: 10806 Human

Entrez Gene: 76816 Mouse

Entrez Gene: 305002 Rat

Omim: 613524 Human

SwissProt: Q86SQ7 Human

SwissProt: Q80UF4 Mouse

Unigene: 591530 Human

Unigene: 171399 Mouse

Unigene: 205402 Rat



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