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CIAPIN1 Rabbit pAb (bs-5764R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產(chǎn)品編號 bs-5764R
英文名稱 CIAPIN1 Rabbit pAb
中文名稱 細胞因子誘導凋亡抑制因子1
別    名 Anamorsin; CIAPIN 1; Cytokine induced apoptosis inhibitor 1; DRE2; CPIN1_HUMAN.  
研究領域 腫瘤  細胞生物  免疫學  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse (predicted: Rat,Pig,Cow)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CIAPIN1: 51-150/312 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 CIAPIN1 (Cytokine induced apoptosis inhibitor 1) expression is dependent on growth factor stimulation. Overexpression confers resistance to apoptosis caused by IL3 deprivation. It may be required during hematopoiesis to mediate antiapoptotic effects of various cytokines. It also confers multidrug resistance in gastric cancer cells by upregulating the expression of MDR1 and MRP1.

Function:
May be required for the maturation of extramitochondrial Fe/S proteins (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity).

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitously expressed. Highly expressed in heart, liver and pancreas.

Similarity:
Belongs to the anamorsin family.

SWISS:
Q6FI81

Gene ID:
57019

Database links:

Entrez Gene: 57019 Human

Entrez Gene: 109006 Mouse

Omim: 608943 Human

SwissProt: Q6FI81 Human

SwissProt: Q8WTY4 Mouse

Unigene: 4900 Human

Unigene: 27582 Mouse



產(chǎn)品圖片
Sample: Heart (mouse) Cell Lysate at 40 ug Primary: Anti- CIAPIN1(bs-5764R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34kD Observed band size: 36 kD
Sample: Hcclm3 (human)cell Lysate at 40 ug Primary: Anti- CIAPIN1(bs-5764R)at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 34kD Observed band size: 36 kD
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