| 產品編號 | bs-4040R |
| 英文名稱 | IL18BP Rabbit pAb |
| 中文名稱 | 白細胞介素18結合蛋白抗體 |
| 別 名 | IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Tadekinig alfa; I18BP_HUMAN; IL-18BP; Interleukin-18-binding protein |
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Specific References (2) | bs-4040R has been referenced in 2 publications.
[IF=5.41] Businaro, Rita, et al. "Interleukin-18 modulation in autism spectrum disorders." Journal of Neuroinflammation 13.1 (2016): 2. WB ; Mouse.
[IF=5.102] Serafino Ricci 2016-01-05. (2016) J.Neuroinflammation. http://www.jneuroinflammation.com/content/13/1/2 WB ; Mouse.
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| 研究領域 | 腫瘤 細胞生物 免疫學 轉錄調節(jié)因子 結合蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Mouse,Rat (predicted: Human,Pig,Cow) |
| 產品應用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 18 kDa |
| 檢測分子量 | |
| 細胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL18BP: 91-194/194 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產品介紹 |
IL18 binding protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18 induced IFN gamma production. It is constitutively expressed and secreted in mononuclear cells and can be enhanced by IFN gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn disease. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. Function: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. Subcellular Location: Secreted. Tissue Specificity: Strongly expressed in heart, lung, placenta and spleen. Similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. SWISS: O95998 Gene ID: 10068 Database links: Entrez Gene: 10068 Human Omim: 604113 Human SwissProt: O95998 Human Unigene: 591967 Human Unigene: 20083 Rat |
| 產品圖片 |
Sample:
Lane 1: Mouse Lymph node tissue lysates
Lane 2: Mouse Placenta tissue lysates
Lane 3: Mouse Large intestine tissue lysates
Lane 4: Rat Lymph node tissue lysates
Lane 5: Rat Lung tissue lysates
Lane 6: Rat Placenta tissue lysates
Lane 7: Ra
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| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
