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Cytochrome P450 2B6 Rabbit pAb (bs-2352R)  
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產(chǎn)品編號 bs-2352R
英文名稱 Cytochrome P450 2B6 Rabbit pAb
中文名稱 細(xì)胞色素P450 2B6抗體
別    名 11B1; CP2B6_HUMAN; CPB 6; CPB6; CYP 2B6; CYP IIB6; CYP2B; CYP2B6; CYP2B7; CYP2B7P; CYPIIB6; Cytochrome P450 2B6; Cytochrome P450 family 2 subfamily B; Cytochrome P450 family 2 subfamily B polypeptide 6; Cytochrome P450 IIB1; Cytochrome P450 phenobarbital inducible; Cytochrome P450 subfamily IIB(phenobarbital inducible); Cytochrome P450 subfamily IIB(phenobarbital inducible) polypeptide 6; Cytochrome P450 subfamily IIB polypeptide 6; 1, 4-cineole 2-exo-monooxygenase; IIB1; P450; P450 IIB1; P450IIB1.  
Specific References  (1)     |     bs-2352R has been referenced in 1 publications.
[IF=2.8] Man, Shuli, et al. "Combination therapy of cyclophosphamide and Rhizoma Paridis Saponins on anti-hepatocarcinoma mice and effects on cytochrome p450 enzyme expression." Steroids (2013).  WB ;  Rat.  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  新陳代謝  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse (predicted: Rat,Rabbit,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,Flow-Cyt=2ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Cytochrome P450 2B6: 401-491/491 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Function:
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase.

Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Tissue Specificity:
Expressed in liver, lung and heart right ventricle.

Post-translational modifications:
Phosphorylation is accompanied by a decrease in enzyme activity (By similarity).

Similarity:
Belongs to the cytochrome P450 family.

SWISS:
P20813

Gene ID:
1555

Database links:

Entrez Gene: 1555 Human

Omim: 123930 Human

SwissProt: P20813 Human

Unigene: 1360 Human



產(chǎn)品圖片
Sample: Liver (Mouse) Lysate at 40 ug Primary: Anti-Cytochrome P450 2B6 (bs-2352R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD
Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti-Cytochrome P450 2B6 (bs-2352R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD
Blank control:U937. Primary Antibody (green line): Rabbit Anti-Cytochrome P450 2B6 antibody (bs-2352R) Dilution: 2μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-PE Dilution: 1μg /test.
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